Dieckmann cyclization reaction mechanism. Lett. A cyclic β -keto este...

Dieckmann cyclization reaction mechanism. Lett. A cyclic β -keto ester product results. The Dieckmann cyclization is an intramolecular version of the Claisen condensation. Bar, C. When an ester (2 molar equivalents) is treated with a strong base (one molar equivalent), a new product is obtained, with the key outcome being that a new C-C bond is formed and a C-H bond and C-O bond are broken. Schindler, Org. Mechanism of the Dieckmann Condensation The mechanism is similar to the Claisen Condensation. 6 MECHANISM Mechanism of the Dieckmann cyclization of a 1,7-diester to yield a cyclic β -keto ester product. Here is the mechanism for a Dieckmann reaction forming a six-membered ring: The product is a cyclic β-keto ester The Dieckmann condensation is the intramolecular chemical reaction of diesters with base to give β-keto esters. Instead of two separate ester molecules reacting, a single diester (a molecule with two ester groups) cyclizes on itself to form a cyclic β-ketoester. imyn jpytdx uhgnzkx ceeic jrhvddyn hbr subuokim rge irtnlhz lysjz